About the Role
What if your years of clinical trial expertise could directly influence how AI reasons about medical evidence, patient outcomes, and regulatory science? We're looking for a Principal Clinical Scientist to bring senior-level clinical knowledge into the development of cutting-edge AI systems — helping ensure the models shaping the future of biomedical research actually get the science right.
This is a fully remote, flexible contract role built for experienced clinical scientists who want to do meaningful work on their own terms. No AI background needed — just deep expertise in clinical research and regulatory standards.
- Organization: Alignerr
- Type: Hourly Contract
- Location: Remote
- Commitment: 10–40 hours/week
What You'll Do
- Design and review clinical trial protocols used to generate high-quality, regulator-ready training datasets for AI systems
- Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
- Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent regulatory expectations
- Provide expert feedback that directly shapes how AI models reason about clinical trial data, study design, and real-world outcomes
- Flag methodological gaps, statistical inconsistencies, or regulatory misalignments in AI outputs
- Work independently and asynchronously — on your schedule, at your pace
Who You Are
- Senior clinical scientist with hands-on experience designing clinical trial protocols for regulatory submission
- Deep expertise interpreting clinical data for major regulatory agencies (FDA, EMA, or equivalent)
- Strong command of clinical research methodology, biostatistics, or translational science
- Rigorous, detail-oriented, and confident making complex scientific judgments
- Clear and precise written communicator who can document feedback systematically
Nice to Have
- Prior experience with data annotation, data quality review, or AI evaluation workflows
- Background in pharmacology, epidemiology, medical affairs, or health outcomes research
- Experience authoring or reviewing regulatory submissions (INDs, NDAs, CTDs, or similar)
- Familiarity with AI tools or clinical decision support systems as an end user
Why Join Us
- Work directly on frontier AI systems making an impact on clinical and biomedical research
- Fully remote and flexible — work when and where it suits you
- Freelance autonomy with the structure of meaningful, expert-level task-based work
- Influence how AI understands, evaluates, and communicates real-world clinical evidence
- Collaborate with world-leading AI research teams and labs
- Potential for ongoing work and contract extension as new projects launch