About the Role
What if your expertise in clinical trial design and regulatory science could directly shape how AI reasons about clinical evidence — influencing the systems that will power the next generation of biomedical research?
We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research workflows. You'll work alongside world-leading AI research teams to ensure that clinical data used to train and evaluate advanced AI systems meets the standards expected in real-world regulatory submissions.
This is a fully remote, flexible contract role built for seasoned clinical scientists who want to do meaningful, frontier work — on their own schedule.
- Organization: Alignerr
- Type: Hourly Contract
- Location: Remote
- Commitment: 10–40 hours/week
What You'll Do
- Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training
- Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
- Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent regulatory expectations
- Provide structured expert feedback that directly improves how AI models reason about clinical trial data, endpoints, and outcomes
- Help establish the scientific standards that define how frontier AI understands clinical evidence
Who You Are
- Senior-level clinical scientist with hands-on experience designing trial protocols for regulatory submission
- Deep expertise interpreting clinical data for major regulatory agencies (FDA, EMA, or equivalent)
- Strong grounding in clinical research methodology, biostatistics, translational science, or a related discipline
- Meticulous, detail-oriented, and comfortable working independently with minimal oversight
- Able to translate complex regulatory and clinical concepts into clear, structured written feedback
Nice to Have
- Prior experience with data annotation, data quality evaluation, or AI training workflows
- Background in pharmacovigilance, health technology assessment, or evidence synthesis
- Familiarity with AI tools or clinical decision support systems as an end user
Why Join Us
- Work directly on frontier AI systems making a real impact on clinical and biomedical research
- Fully remote and flexible — work when and where it suits you
- Freelance autonomy with the structure of meaningful, project-based work
- Influence how AI understands, evaluates, and reasons about real-world clinical evidence
- Collaborate with leading AI research teams and labs on cutting-edge projects
- Potential for ongoing work and contract extension as new projects launch