About the Role
What if your decades of clinical trial expertise could directly influence how AI reasons about medical evidence, regulatory submissions, and patient outcomes? We're looking for a Principal Clinical Scientist to bring senior-level rigor to one of the most consequential frontiers in technology — AI systems that interpret and generate clinical data.
This is a fully remote, flexible contract role built for experienced clinical scientists who want to make an outsized impact without the constraints of a traditional position. You'll work alongside leading AI research labs to ensure that frontier models handle clinical evidence the way regulators — and patients — deserve.
- Organization: Alignerr
- Type: Hourly Contract
- Location: Remote
- Commitment: 10–40 hours/week
What You'll Do
- Design and critically review clinical trial protocols used to generate high-quality, regulator-ready training datasets for AI systems
- Interpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory standards (FDA, EMA, or equivalent)
- Evaluate AI-generated clinical analyses for scientific soundness and regulatory relevance — catching errors that only a seasoned expert would spot
- Provide structured, expert feedback that directly shapes how AI models reason about clinical trial design, data, and outcomes
- Help establish the gold standard for how AI understands and communicates clinical evidence
Who You Are
- Senior-level clinical scientist with hands-on experience designing clinical trial protocols for regulatory submission
- Deep expertise interpreting clinical data for regulatory agencies such as the FDA, EMA, or equivalent bodies
- Strong grounding in clinical research methodology, biostatistics, or translational science
- Naturally detail-oriented — you hold clinical evidence to the highest standard and notice when something doesn't hold up
- Comfortable working independently in an asynchronous, remote environment
Nice to Have
- Prior experience with data annotation, data quality frameworks, or evaluation systems
- Background in AI, digital health, or clinical decision support tools
- Experience across multiple therapeutic areas or trial phases
- Familiarity with ICH guidelines, GCP standards, or submission dossier preparation
Why Join Us
- Work directly on frontier AI systems that will shape the future of clinical and biomedical research
- Fully remote and flexible — structure your work around your life, not the other way around
- Freelance autonomy with the substance of genuinely meaningful, high-stakes work
- Influence how AI systems understand, evaluate, and communicate real-world clinical evidence at scale
- Collaborate with world-class AI research teams and labs on cutting-edge projects
- Potential for ongoing work and contract extension as new projects launch