Back to jobs

Principal Clinical Scientist

$40-80/hrRemoteFreelanceSTEM

About the Role

What if your decades of clinical trial expertise could directly influence how AI reasons about medical evidence, regulatory submissions, and patient outcomes? We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research workflows — ensuring the clinical data powering next-generation AI systems meets the standards that matter in the real world.

This is a fully remote, flexible contract role built for experienced clinical scientists who want to do meaningful work on their own terms.

  • Organization: Alignerr
  • Type: Hourly Contract
  • Location: Remote
  • Commitment: 10–40 hours/week

What You'll Do

  • Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training and evaluation
  • Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
  • Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent regulatory standards
  • Provide expert, structured feedback that directly improves how AI models reason about clinical trial data and outcomes
  • Work independently and asynchronously — fully on your own schedule

Who You Are

  • Senior-level clinical scientist with hands-on experience designing trial protocols for regulatory submission
  • Deep expertise interpreting clinical data for major regulatory agencies (FDA, EMA, or equivalent)
  • Strong grounding in clinical research methodology, biostatistics, translational science, or related disciplines
  • Sharp eye for scientific accuracy, regulatory alignment, and data quality
  • Self-directed and comfortable delivering high-quality work independently

Nice to Have

  • Prior experience with data annotation, data quality assurance, or AI evaluation workflows
  • Background in pharmacovigilance, outcomes research, or clinical evidence synthesis
  • Familiarity with AI tools or clinical informatics platforms

Why Join Us

  • Work directly on frontier AI systems shaping the future of clinical and biomedical research
  • Fully remote and flexible — contribute on a schedule that fits your life
  • Freelance autonomy: set your own pace, work from anywhere, collaborate globally
  • Make a tangible impact on how AI understands and evaluates real-world clinical evidence
  • Potential for ongoing work and contract extension as new projects launch