About the Role
What if your years of clinical trial expertise could directly influence how AI reasons about medical evidence, regulatory submissions, and patient outcomes? We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research workflows — ensuring the clinical data that trains and evaluates next-generation AI systems meets the exacting standards of real-world regulatory practice.
This is a fully remote, flexible contract role built for experienced clinical scientists who want to work at the frontier of biomedical AI without leaving their area of expertise.
- Organization: Alignerr
- Type: Hourly Contract
- Location: Remote
- Commitment: 10–40 hours/week
What You'll Do
- Design and review clinical trial protocols used to generate high-quality, regulator-ready AI training datasets
- Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
- Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent agency expectations
- Provide expert feedback that shapes how AI models reason about clinical trial data, endpoints, and outcomes
- Help establish quality standards for how clinical evidence is represented and evaluated within AI systems
Who You Are
- Senior-level clinical scientist with hands-on experience designing clinical trial protocols for regulatory submission
- Deep expertise interpreting clinical data for regulatory agencies (FDA, EMA, or equivalent)
- Strong grounding in clinical research methodology, biostatistics, or translational science
- Rigorous, detail-oriented thinker who can identify gaps between AI-generated outputs and real-world regulatory standards
- Comfortable working independently and asynchronously in a remote environment
Nice to Have
- Prior experience with data annotation, data quality evaluation, or AI training workflows
- Background in pharmacovigilance, medical affairs, or clinical data management
- Familiarity with ICH guidelines, GCP, or similar regulatory frameworks
- Experience reviewing or contributing to regulatory dossiers or clinical study reports
Why Join Us
- Work directly on frontier AI systems shaping the future of clinical and biomedical research
- Fully remote and flexible — structure your hours around your existing commitments
- Freelance autonomy with the substance of high-impact, intellectually demanding work
- Influence how AI understands, evaluates, and reasons about real-world clinical evidence
- Collaborate with leading AI research teams and labs at the cutting edge of the field
- Potential for ongoing work and contract extension as new projects launch