About the Role
What if your career-long expertise in clinical trial design and regulatory science could directly influence how AI reasons about medicine, data, and patient outcomes?
We're looking for a Principal Clinical Scientist to bring senior-level rigor to one of the most consequential challenges in AI development: ensuring that AI systems trained on clinical data actually understand it the way regulators, researchers, and clinicians do.
This is a fully remote, flexible contract role built for experienced clinical scientists who want to work at the frontier of AI and biomedical research — on their own terms.
- Organization: Alignerr
- Type: Hourly Contract
- Location: Remote
- Commitment: 10–40 hours/week
What You'll Do
- Design and critically review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training
- Interpret and audit clinical trial results for accuracy, consistency, and alignment with regulatory standards
- Evaluate AI-generated clinical analyses for scientific soundness and compliance with FDA, EMA, or equivalent agency expectations
- Provide expert, structured feedback that directly improves how AI models reason about clinical evidence, trial methodology, and outcomes
- Flag gaps, inconsistencies, or methodological errors in AI-generated clinical content
- Work independently and asynchronously — fully on your own schedule
Who You Are
- Senior-level experience designing clinical trial protocols for regulatory submission — you've done this at a high level in the real world
- Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent regulatory bodies
- Strong grounding in clinical research methodology, biostatistics, or translational science
- Naturally rigorous and detail-oriented — you hold AI-generated content to the same standards you'd apply to a real submission
- Clear and precise written communicator who can articulate complex scientific reasoning in structured feedback
Nice to Have
- Prior experience with data annotation, data quality assurance, or evaluation systems
- Background in regulatory affairs, clinical operations, or medical writing
- Familiarity with AI tools or scientific evaluation workflows
- Experience working across therapeutic areas or with international regulatory submissions
Why Join Us
- Work directly on frontier AI systems that are reshaping clinical and biomedical research
- Influence how AI understands, evaluates, and reasons about real-world clinical evidence — at scale
- Fully remote and flexible — work when and where it suits you
- Freelance autonomy with the structure of meaningful, high-impact work
- Collaborate with world-leading AI research teams and labs
- Potential for ongoing work and contract extension as new projects launch