About the Role
What if your expertise in clinical trial design and regulatory science could directly shape how AI understands and interprets biomedical evidence? We're looking for a Principal Clinical Scientist to bring senior-level clinical rigor to cutting-edge AI research — helping ensure that the AI systems influencing the future of medicine are built on scientifically sound, regulatory-grade foundations.
This is a fully remote, flexible contract role designed for experienced clinical scientists who want to do meaningful work at the intersection of clinical research and frontier AI.
- Organization: Alignerr
- Type: Hourly Contract
- Location: Remote
- Commitment: 10–40 hours/week
What You'll Do
- Design and review clinical trial protocols used to generate high-quality, regulatory-ready datasets for AI training and evaluation
- Interpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory standards
- Evaluate AI-generated clinical analyses for scientific soundness and compliance with the expectations of agencies such as the FDA, EMA, or equivalent bodies
- Provide expert, structured feedback that directly improves how AI models reason about clinical trial data, endpoints, and outcomes
- Apply your knowledge of clinical research methodology to identify gaps, errors, and areas for improvement in AI-generated outputs
Who You Are
- Senior-level clinical scientist with hands-on experience designing clinical trial protocols for regulatory submission
- Deep expertise interpreting clinical data in the context of FDA, EMA, or equivalent regulatory frameworks
- Strong grounding in clinical research methodology, biostatistics, translational science, or a closely related discipline
- Sharp eye for scientific accuracy and regulatory relevance — you know when something doesn't meet the bar
- Self-motivated, reliable, and comfortable working independently in an asynchronous environment
Nice to Have
- Prior experience with data annotation, data quality workflows, or AI evaluation systems
- Background in pharmacovigilance, medical writing, or health technology assessment
- Familiarity with AI tools or scientific content evaluation platforms
- Experience working across therapeutic areas or with cross-functional regulatory teams
Why Join Us
- Work directly on frontier AI systems that are shaping the future of clinical and biomedical research
- Influence how AI understands, evaluates, and reasons about real-world clinical evidence
- Fully remote and flexible — work when and where it suits you
- Freelance autonomy with the structure of meaningful, expert-level work
- Collaborate with world-leading AI research teams and labs
- Potential for ongoing work and contract extension as new projects launch