About the Role
What if your expertise in clinical trial design and regulatory science could directly shape how AI reasons about biomedical evidence for millions of people worldwide? We're looking for a Principal Clinical Scientist to bring senior-level rigor to cutting-edge AI research — ensuring the clinical data that trains and evaluates next-generation AI systems meets the highest standards of scientific and regulatory quality.
This is a fully remote, flexible contract role built for experienced clinical scientists who want to do meaningful work at the intersection of medicine and frontier AI — on their own schedule.
- Organization: Alignerr
- Type: Hourly Contract
- Location: Remote
- Commitment: 10–40 hours/week
What You'll Do
- Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training and evaluation
- Interpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory expectations (FDA, EMA, or equivalent)
- Evaluate AI-generated clinical analyses for scientific soundness and methodological integrity
- Provide expert, structured feedback that directly improves how AI models reason about clinical trial data, outcomes, and evidence
- Help establish and uphold the quality standards that govern clinical data used in AI-driven research workflows
Who You Are
- Senior-level experience designing clinical trial protocols for regulatory submission
- Deep expertise interpreting clinical data for major regulatory agencies such as the FDA, EMA, or equivalent bodies
- Strong background in clinical research methodology, biostatistics, or translational science
- Sharp analytical mind with a rigorous, detail-oriented approach to evaluating data quality and scientific validity
- Able to communicate complex clinical concepts clearly and precisely in written feedback
- Self-directed and comfortable working independently in an asynchronous environment
Nice to Have
- Prior experience with data annotation, data quality assurance, or AI evaluation systems
- Familiarity with AI tools or clinical informatics platforms
- Background in oncology, rare disease, or other complex therapeutic areas
- Experience working across multi-site or international clinical research settings
Why Join Us
- Work directly on frontier AI systems that are reshaping clinical and biomedical research
- Influence how AI understands, evaluates, and communicates real-world clinical evidence
- Fully remote and flexible — work when and where it suits you
- Freelance autonomy with the structure of meaningful, high-impact project work
- Collaborate with leading AI research teams and labs on a global scale
- Potential for ongoing work and contract extension as new projects launch