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Principal Clinical Scientist

$40-80/hrRemoteFreelanceSTEM

About the Role

What if your career-long expertise in clinical trial design and regulatory science could directly influence how AI understands and evaluates medical evidence?

We're looking for a Principal Clinical Scientist to bring senior-level rigor to the AI systems being built at the frontier of biomedical research. You'll work alongside world-leading AI labs to ensure that clinical data powering next-generation AI models meets the standards expected in real-world regulatory submissions.

This is a fully remote, flexible contract role — work on your own schedule, on your own terms.

  • Organization: Alignerr
  • Type: Hourly Contract
  • Location: Remote
  • Commitment: 10–40 hours/week

What You'll Do

  • Design and critically review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training and evaluation
  • Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
  • Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent regulatory standards
  • Provide expert, structured feedback that directly shapes how AI models reason about clinical data, trial outcomes, and biomedical evidence
  • Identify gaps, errors, or misalignments between AI outputs and real-world regulatory expectations

Who You Are

  • Senior-level clinical scientist with hands-on experience designing clinical trial protocols for regulatory submission
  • Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or their international equivalents
  • Strong grounding in clinical research methodology, biostatistics, or translational science
  • Rigorous, detail-oriented, and comfortable working independently on complex scientific material
  • Clear and precise written communicator — you can articulate nuanced scientific judgment in structured formats

Nice to Have

  • Prior experience with data annotation, data quality evaluation, or AI model assessment workflows
  • Background in pharmacovigilance, medical affairs, or health technology assessment
  • Familiarity with AI tools or scientific evaluation platforms as an end user

Why Join Us

  • Work directly on frontier AI systems making a real impact in clinical and biomedical research
  • Influence how the next generation of AI understands, evaluates, and reasons about real-world clinical evidence
  • Fully remote and flexible — work when and where it suits you, with no fixed schedule
  • Freelance autonomy with the substance of high-impact, expert-level scientific work
  • Collaborate with leading AI research teams on problems that matter
  • Potential for ongoing work and contract extension as new projects launch