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Principal Clinical Scientist

$40-80/hrRemoteFreelanceSTEM

About the Role

What if your decades of clinical trial expertise could directly shape how AI reasons about medical evidence, regulatory data, and patient outcomes? We're looking for a Principal Clinical Scientist to bring senior-level rigor to the AI systems that are rapidly transforming biomedical research.

At Alignerr, we partner with the world's leading AI research teams to build and train cutting-edge models. In this role, your expertise in regulatory-grade trial design and clinical data interpretation won't just inform internal processes — it will influence how next-generation AI understands and evaluates real-world clinical evidence.

This is a fully remote, flexible contract role designed for senior clinical scientists who want meaningful, high-impact work on their own schedule.

  • Organization: Alignerr
  • Type: Hourly Contract
  • Location: Remote
  • Commitment: 10–40 hours/week

What You'll Do

  • Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training and evaluation
  • Interpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory standards
  • Evaluate AI-generated clinical analyses for scientific soundness and regulatory relevance
  • Provide structured expert feedback that directly improves how AI models reason about clinical trial data, endpoints, and outcomes
  • Help establish quality benchmarks for clinical content used across frontier AI systems

Who You Are

  • Senior-level professional with hands-on experience designing clinical trial protocols for regulatory submission
  • Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent regulatory bodies
  • Strong grounding in clinical research methodology, biostatistics, or translational science
  • Meticulous, structured thinker who can communicate complex scientific judgments clearly and consistently
  • Self-directed and comfortable working independently in an async, remote environment

Nice to Have

  • Prior experience with data annotation, data quality assurance, or AI evaluation workflows
  • Background in clinical pharmacology, outcomes research, or medical affairs
  • Familiarity with AI tools or experience reviewing AI-generated scientific content

Why Join Us

  • Work directly on frontier AI systems making a real impact on clinical and biomedical research
  • Fully remote and flexible — work when and where it suits you
  • Freelance autonomy with the structure of meaningful, expert-level work
  • Collaborate with world-class AI research teams on problems that matter
  • Potential for ongoing work and contract extension as new projects launch